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However, it remains investigational

No impact on bone fractures : If osteoporosis is a concern, the GLP-1 receptor agonists were shown not to increase fracture rates.[ref] Benefits for CVD : In a huge cardiovascular disease study, GLP-1 RAs were shown to be associated with a lower risk of heart attacks and strokes.[ref] Works best with Exercise: A randomized clinical trial found that GLP-1 RAs work best for weight loss when combined with exercise

High sensitivity means a meal goes toward refilling glycogen and supporting repair

The European journal of neuroscience

Second, the follow-up durations in several trials were insufficient to assess long-term carcinogenesis

However, the weight loss possible with Wegovy will also lead to substantial improvement of overall health and decrease in health risks for most obese people