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Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1c targets

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Studies have found that all GLP-1 treatments can lead to weight loss of about 10.5 to 15.8 pounds

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The two most effective bariatric procedures, Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) both result in enhanced meal-stimulated GLP-1 release which may be contributing to improvements in glucose metabolism and weight loss induced by these procedures

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2016: The FDA New Drug Application is filed

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