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Bottom line (short) Tirzepatide is a novel dual GIP/GLP-1 receptor agonist that produces substantially greater average weight loss (in SURMOUNT-1 up to ~21% with 15 mg at 72 weeks) than placebo and larger weight and A1c reductions than some comparator GLP-1 therapies in trials

Besides dopamine and oxytocin, two sex hormones also play a role in libido

Follow the pump manufacturers instructions and your diabetes teams backup plan for unexplained high readings, infusion-site problems, or device alarms

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GLP-1 receptor agonists mimic the action of naturally occurring hormones that regulate blood glucose and appetite by: Slowing gastric emptying, promoting feelings of fullness Reducing appetite signals in the brains hunger centers Improving insulin secretion while suppressing glucagon release Creating a caloric deficit through reduced food intake Originally developed for type 2 diabetes management, these medications have gained FDA approval for chronic weight management in adults with obesity or overweight with weight-related comorbidities

Manage Stress: High-stress levels can affect your digestive system and exacerbate bloating