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Belonging to the glucagon-like peptide-1 (GLP-1) receptor agonist class of drugs, they share certain similarities but also exhibit notable differences

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Carbohydrates stay low-glycemic GLP-1 receptor agonists improve insulin sensitivity and blood sugar regulation

Butyrate crosses the blood-brain barrier and has documented effects on appetite regulation, neuroinflammation, and mood

J Clin Anesth 2023;87:111091

However, weight reduction effect of tirzepatide have renewed interest in the GIP role within dual agonists for GLP-1 and GIP receptors