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Effectiveness: In one double-blind trial , participants taking 2.4 mg of semaglutide (the maximum dosage of Wegovy) over 68 weeks lost 14.9% of their body weight

A large meal that would normally leave the stomach in two hours might sit there for three or four, creating that uncomfortable fullness and nausea that many people report

It is also approved for adults who are overweight with at least one weight-related health condition, such as diabetes or high blood pressure
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It also controls appetite and reduces caloric intake by slowing gastric emptying and sending signals to the brain that youre full

Participants maintained A1C reductions throughout the study duration, and there was no indication that the medication's glucose-lowering effects diminished over time at stable maintenance doses