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Unopened tirzepatide pens should be stored in the refrigerator at 2 to 8 degrees Celsius (36 to 46 degrees Fahrenheit)

Q4 2025 at a glance Revenue: $19.3B (+43% YoY) Reported EPS: $7.39 (+51%) | Non-GAAP EPS: $7.54 Growth driven primarily by @Mounjaro and @Zepbound volume expansion Pipeline & regulatory highlights FDA approval of tirzepatide KwikPen Expanded indication for @Jaypirca (pirtobrutinib) Regulatory submissions for orforglipron (oral GLP-1) in the U.S., Japan, and EU Positive Phase 3 data across obesity, psoriatic arthritis, osteoarthritis, and oncology programs Manufacturing & access strategy Continued global manufacturing expansion New agreement with the U.S

Avoid eating or drinking for 15 minutes before and after taking this medication

However, the body must work harder to process two systemic medications, which is why personalized medical guidance is essential

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Effective product chemistry also considers how ingredients work together: The stability, absorption, pH levels, and supporting compounds determine whether a product actually performs once it touches your skin