semaglutide nejm weight loss Oral at a Dose of 25 mg in Adults with Overweight or Obesity RT @MichaelAlbertMD: 🚨 Oral Semaglutide

ONGOING TRIALS Currently, a limited number of clinical trials are exploring how SGLT-2is may influence gut microbiota composition

The Fallout (and Whats Coming) Theres been an explosion of weight loss clinics, while compounding pharmacies are closing at an alarming rate

J Am Soc Nephrol 2019

Cellulaze This FDA-cleared, minimally invasive method heats the tissue beneath the skins surface to improve texture and elasticity, stimulate collagen production, and reduce fat in the subcutaneous fat layer

The theoretical argument is simple: going sub q bypasses the gut and first-pass metabolism entirely, so in theory youd get close to 100% bioavailability versus the ~38% seen orally

Other health factors: sleep, stress, menopause, thyroid disease, steroids, some antidepressants and other medicines can affect appetite, water retention or weight