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Discussion In the current systematic review and meta-analysis, 10 RCTs were analyzed to evaluate the effectiveness and safety of combination therapy with SGLT-2i and GLP-1RA compared to monotherapy of each individually on the incidence of MACE and hospitalization for heart failure

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doi: 10.1007/s00125-024-06243-z

Nature 510, 542546

C187H291N45O59 How GLP-1 S clears from circulation, modeled from its documented ~~165 hours (~7 days) half-life

There are diners who prefer almost raw fish so they eat it immediately, others prefer the fish to be cooked and for them 10 minutes is fine
