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Serious adverse events were reported in 11% of participants in the semaglutide group and 9% of participants in the placebo group [49]

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For many people, the weight-loss journey with semaglutide extends beyond the initial 5 to 6 months

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The rising appeal of GLP-1 drugs for cosmetic weight loss has led to a significant increase in off-label prescribing, which can result in unnecessary claims, legal or ethical dilemmas and the risk of poor health outcomes for individuals who may not receive the right support for their condition

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The risk can be lowered by reducing the dose of sulfonylurea or insulin when initiating treatment with semaglutide." Complications can also arise for those on Ozempic who have diabetic retinopathy that is treated with insulin and semaglutide

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