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The approval was based on data from the SUNSHINE and SUNRISE studies, which together showed that Cosentyx-treated patients achieved significantly higher rates of clinical response compared to placebo

GLP-1R are found, apart from the pancreas, in lungs, kidney, central nervous system, stomach, cardiomyocytes, and vascular endothelial cells (13)

Research into the possible modulation of GLP-1 activity is currently underway, focusing on plants that have been used for centuries in traditional medicine to control diabetes [186]

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Global Burden of Cardiovascular Diseases and Risk Factors, 19902019

GLP-1 receptor agonistinduced diabetic ketoacidosis: A case report