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ClinicalTrials.gov, NCT05929066: A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight, record last updated June 3, 2026
Leidy HJ, et al
GLP-1 Medications and NAION: What Patients Should Know About Sudden Vision Loss David B
A study from 2024 also showed that people on tirzepatide were more likely to experience greater weight loss
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Even the 4 mg dose reached with a single escalation step produced 19.0% weight loss with lower discontinuation than placebo, supporting Lillys segmentation strategy across tolerability, personalization, and longterm management
