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doi: 10.1016/j.regpep.2010.05.008 [DOI] [PubMed] [Google Scholar] 40.Tang C, Li Q, Deng X, et al

21st ed
Patients should seek medical evaluation if they experience: Persistent symptoms despite adequate levothyroxine replacement (confirmed by normal TSH) Rapid thyroid enlargement or development of thyroid nodules Difficulty swallowing or breathing related to thyroid enlargement Symptoms suggesting thyroid hormone over-replacement (palpitations, tremor, anxiety, heat intolerance) Regular monitoring of thyroid function is essential for patients with Hashimoto's disease

Because of its wide-ranging systemic effects, many mediated by gut microbial metabolites such as short-chain fatty acids (SCFAs), adequate dietary fiber intake is essential for maintaining homeostasis

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