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Semaglutide can lose 10, 20, even 30 percent of its potency without showing any visible change

This shift introduces a new challenge for R&D teams: sterilization as a constraint that can influence what types of therapies are feasible to develop and deliver
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These findings are investigational

Vital signs Blood pressure and heart rate were stable during the trial, mean arterial pressure was lower at 12 weeks in the exenatide group compared to placebo, 6.7 mmHg (3.6), P = 0.088, but there was no significant change within arms between baseline and 12 weeks (Supplementary Table 4)

The FDA has updated Ozempics label to warn about gastrointestinal obstruction and gastroparesis, a condition involving delayed stomach emptying
