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The review found that semaglutide and tirzepatide showed the highest reported rates of hair loss signals among GLP-1 therapies , with telogen effluvium and androgenetic alopecia being the most commonly reported hair-loss patterns

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Clinical trials show semaglutide (Wegovy) produces average weight loss of approximately 15% over 68 weeks, liraglutide (Saxenda) around 810% over one year, and tirzepatide over 20% in some participants, all combined with lifestyle interventions