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Description
Methods Retrospective study utilizing data from a federated research network (TriNetX)

In terms of switching, 22.9% of the GLP-1 receptor agonist users and 2.1% of the SGLT2 inhibitor users switched between drugs within the same drug class
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Drugs known as GLP-1 receptor agonists were initially developed to treat Type 2 diabetes but have become a cultural phenomenon.

Group one included patients with moderate PAD who were started on GLP-1 RAs, and group two included patients with moderate PAD who were not started on GLP-1 RAs. At one year, patients with moderate PAD who were started on GLP-1 RAs had fewer major adverse limb events (MALE) (0.8% vs 1.5%), major adverse cardiac events (MACE) (25.4% vs 29.3%), and decreased risk of hospitalizations (17.9 vs 26.8%)
