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These results came from a population with obesity and knee osteoarthritis, not a lean or highly motivated trial-completer group

Scientists call for ethical non-animal nutrition research A review by the Physicians Committee for Responsible Medicine (PCRM) critiqued the widespread use of animals in US nutrition research, calling for a shift to non-animal methods (NAMs)

They are not recommended in those with personal or family history of multiple endocrine neoplasia 2A, multiple endocrine neoplasia 2B, or medullary thyroid cancer due to concern for long-term thyroid effects.3 Side Effects and their Implications in the ED Gastrointestinal Side effects Mild gastrointestinal side effects are most common with patients experiencing nausea (25-40%), vomiting, diarrhoea, or constipation.3,4 Rarer, more serious presentations include pancreatitis, bowel obstruction, gallbladder disease, which should be actively managed in the ED.3,5 Hypersensitivity reaction These reactions are commonly associated with self-limiting or antihistaminic responsive pruritic rash

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