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Consequently, it is not available through NHS prescribing channels, and there is no NICE-approved guidance on its use, dosage, or patient selection criteria

Now Markert, who switched to Blue Cross this year, will pay $500 a month out of pocket, the equivalent of a car payment

The medication does not lose its edge

doi: 10.1093/eurheartj/ehw110

When patients understand both the metabolic benefits and the potential hepatobiliary risks, they are more likely to engage in proactive symptom reporting

This extended use is considered off-label, which means: The medication is used beyond the FDA-approved duration The practice is legal It is often supported by clinical experience and emerging evidence Phentermine was originally approved in 1959, an era when long-term obesity trials were uncommon