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Diabetes Care 34(Suppl 2):S279-284

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What's Different And Worth Taking Seriously: The glucagon receptor agonism in retatrutide introduces effects that tirzepatide users haven't had to manage: Heart rate elevation: Retatrutide's Phase 2 data showed a mean increase in resting heart rate of approximately 56 beats per minute at higher doses

Gastric pacing by high-energy, low-frequency GES (long pulses) attempts to restore the regular slow wave rhythm of 3 cycles/min of normal gastric myoelectric activity and has been found to improve symptoms and gastric emptying [5]

10.1016/j.ajps.2019.01.002

A thorough assessment should include review of other medications (antidepressants, antihypertensives, and hormonal contraceptives commonly affect sexual function), evaluation for mood disorders including depression and anxiety, assessment of relationship factors and psychosocial stressors, and consideration of underlying medical conditions such as thyroid dysfunction, diabetes complications, or cardiovascular disease