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Recombinant CHO-K1 cells stably overexpress human glucagon-like peptide-1 receptor (GLP1R) on the surface and contain high levels of G protein Gs to couple with the receptor in downstream signaling pathways.
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US pharma giant Pfizer presented detailed results from multiple Phase IIb studies of berobenatide (PF-3944), an investigational, potential first-in-class monthly GLP-1 receptor agonist (GLP-1 RA) peptide, during a late-breaking expert symposium at the 86th Scientific Sessions of the American Diabetes Association (ADA).
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