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When your cells stop responding to insulin (the hormone that moves sugar out of your bloodstream), your body stores those calories as fat instead

The phase 3 trials also tested a 4mg maintenance dose in addition to the 9mg and 12mg doses

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In the SURPASS trials for diabetes, HbA1c reductions ranged from 1.82.4%, while the SURMOUNT trials showed weight loss averaging 1522% of body weight in participants with obesity

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