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Concerns regarding an increased risk of acute pancreatitis have emerged based on global studies and post-marketing surveillance data [13, 27]

46 In this study, 9%, 30%, and 59% of the participants had been receiving 3 mg, 7 mg, and 14 mg of once-daily oral semaglutide until week-52

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While anabolic or anti-catabolic agents - especially myostatin/activin pathway inhibitors - show promise, translation into improved patient-centered outcomes is not yet established (Table 3)