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(2025) GLP-1 Agonists in Cardiovascular Diseases: Mechanisms, Clinical Evidence, and Emerging Therapies

The FDA gave pharmacies wind-down periods - 60 days for 503A state-licensed pharmacies, 90 days for 503B outsourcing facilities

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Just as actin dynamics are critical for the biphasic secretion of insulin and the exocytosis of insulin-containing granules from cells, they are equally essential for biphasic GLP-1 exocytosis from L cells 12

doi: 10.1038/s41588-022-01058-3

Poor sleep increases cortisol, drives insulin resistance, increases hunger hormones (even partially overriding GLP-1 appetite suppression), and impairs recovery from exercise