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These findings highlight the importance of TREM2 in promoting microglia polarization to the M2 anti-inflammatory phenotype and alleviating cognitive dysfunction (Wu M

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FUNDING This work was supported by the National Natural Science Foundation of China (82300903), the Key R&D Plan Social Development Project of Jiangsu Province (SBE2023741128), the National Natural Science Foundationof Jiangsu Province (SBK20 23022865), the sixth phase 333 second level talent training project of Jiangsu Province (tackling bottleneck technology) (BRA2022008), the Projects from Social Development of Zhenjiang (SH2023029), the Youth Science and Technology Talent Recruitment Project of Zhenjiang city (ZJTJ2101), the Affiliated Hospital of Jiangsu University Beigu Talent Cultivation Plan Project (BGYCB202206), the Affiliated Hospital of Jiangsu University Doctoral Initiation Fund Project (jdfykc2021005)

PubMed One real-world study showed that patients with type 2 diabetes using GLP-1 RAs had a reduced risk of incident dementia compared with some other second-line diabetes therapies