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Recently, Gaykema et al

Furthermore, GLP-1 RAs have beneficial effects for reducing the risk of MI or endpoints composed of coronary events (e.g., MACE, cardiovascular mortality), while solid evidence on CCS, vasospastic angina, and MVA is lacking

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Cons: Users may experience varied outcomes, and the effectiveness can differ from one individual to another

More importantly, the tumor-promoting effect of insulin in pancreatic cancer cells and the TME is essential, which makes insulin and its related signal pathway a potential novel target for cancer therapies