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This hypothesis is anchored on the observations that GIP is a target of PPAR, a master regulator of adipogenesis (174), the expression of GIP increases during adipocyte differentiation (175, 176), and that knockdown of GIPR impairs adipocyte development (175)

The question now is, can we extrapolate that into other patient populations

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This allows for the evaluation of the overall competition within the market

Retatrutide is the successor to Novo Nordisk's GLP-1 drugs Ozempic/Wegovy (Semaglutide) and Eli Lilly's Mounjaro/Zepbound (Tirzepatide)

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