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Nausea and stomach discomfort can intensify when lying down flat, making it harder to find a comfortable sleeping position

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doi: 10.3390/ijms232314631, Summary Keywords GLP-1/GIP dual agonist, metabolic regulation, obesity, obstructive sleep apnea, tirzepatide Citation Fang Q, Zhu Y, Rao M and Liu P (2026) GLP-1/GIP dual agonist tirzepatide in obstructive sleep apnea syndrome: mechanisms, evidence, and clinical perspectives

Hi, I was on Mounjaro but unfortunately I believe my Afib is sensitive to the Vagus nerve and when my stomach started to bloat, creating extra gas, every time I burped it triggered AFib

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In a double-blind, randomized trial of 44 metformin-treated patients with T2DM, neither dapagliflozin nor gliclazide significantly altered gut microbiome composition over 12 weeks, despite exhibiting divergent metabolic effects such as reduced weight and fasting insulin with dapagliflozin and increased insulin with gliclazide [40]