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With a wealth of data in support of its safety and efficacy, semaglutide stands out among the breakthrough antiobesity drugs that have emerged in response to the obesity epidemic

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P = .001) No significant effect on mental QoL or PANSS-6 scores Adverse Effects GI symptoms more frequent in semaglutide group Slightly higher hospitalization rates in semaglutide group No difference in the number of serious adverse events between groups Clinical Implications This study confirms that semaglutide is safe and highly effective for improving metabolic health in patients with schizophrenia receiving antipsychotics