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Christopher McGowan, who runs a weight loss clinic in Cary, North Carolina, and is Grants doctor

GLP-1 Side Effects When GLP-1 binds to receptors in the brain, it signals the body to release a hormone called cholecystokinin (CCK)

Most patients notice appetite changes within 1-3 weeks, but visible weight loss typically appears between weeks 4-8

Practical implications For patients who develop allodynia on one GLP-1 medication, switching to a different medication within the class (or to a different formulation of the same medication) is a reasonable strategy to try

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At LCS Medical Spa, we understand that achieving a healthy weight can be challenging, even with the best intentions