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Other Possible Serious or Concerning Side Effects Although rare, some studies have reported more serious or unusual adverse events, including: Cardiac arrhythmia Elevated liver enzymes Acute pancreatitis (rare cases) Abnormal skin sensations (dysesthesia) in some trials Because the drug affects several hormone pathways involved in metabolism, researchers say long-term safety data will be essential before approval
Emmerson, P
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Research published in Molecules measured the net desensitization half-life at just 2.99 minutes
OReardon JP, Allison KC, Martino NS, et al
Semaglutide should not be used in individuals with hypersensitivity to the medication or any oral medications or its components
