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People skip doses because of needles, travel, or refrigeration

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In the US, obesity is a major problem that has big effects on people's health and on the whole healthcare system

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Typical usage in research settings is once-weekly injections by subcutaneous route

The authors say the research should serve as a "cautionary tale" about possible long-term health effects of these drugs."If people have been prescribed these drugs, then the benefits should likely far exceed the risks," explained Dr Jason Dyck, senior author on the study, pediatrics professor in the Faculty of Medicine & Dentistry a