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And as more people take the meds, doctors and patients alike are noticing many more unexpected benefits beyond the quieting of food noise

On average, when a GLP-1 receptor agonist is added to diet and exercise for longer than six months, a lowering of HbA 1c by about 1% (11mmol/mol) has been demonstrated, along with weight loss of 1 to 3 kg

It applies the standard MHRA thresholds, then applies the NICE NG246 ethnic adjustment (27.5, or 24.5 with a condition) for the relevant ethnic backgrounds

Weight loss achieved with these medications may result in improvements in blood pressure, fatty liver disease, and other obesity-related conditions, particularly in cases where these conditions are driven by insulin resistance

Similar cardiovascular outcomes in patients with diabetes and established or high risk for cor- onary vascular disease treated with dulaglutide with and without baseline metformin