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Description
(30) Rapid weight loss and volume shifts may contribute to perioperative hemodynamic instability, particularly in older or higher-risk patients
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Then at 50 I started losing weight on a GLP-1, and one warning followed me everywhere I read: a big share of what you drop on these drugs isnt fat, its muscle, and the only thing that protects it is lifting weights

For many, this is selflimiting and temporary

Conclusions and Relevance In this cohort study, most patients with overweight or obesity discontinued GLP-1 RA therapy within 1 year, but those without type 2 diabetes had higher discontinuation rates and lower reinitiation rates

Changes in health-related quality of life and associations with improvements in clinical efficacy: a phase 2 study of mirikizumab in patients with ulcerative colitis
