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Another factor to consider is gastrointestinal tolerance

Nowadays, however, this is less common because effective treatment prevents it from developing

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GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2

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Frias JP, Nauck MA, Van J, Kutner ME, Cui X, Benson C et al
