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OASIS trials had a high proportion of women (73%85%), typical for obesity trials

While rashes are not listed as primary adverse effects in major clinical trials, localized injection site irritation and rare dermatological events do occur in some individuals

However, the *perception* of blood sugar dropping can trigger vasovagal responses: heart rate increases, blood vessels constrict, and dizziness follows even if measured glucose remains safe

Timeline considerations : If you've been at the maximum dose (2.4 mg weekly) for approximately 12 weeks with adherence to dietary and activity recommendations but have lost less than 5% of your starting body weight, this warrants discussion with your healthcare provider

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The role of hydration, electrolytes, and fiber, small levers with big outcomes Hydration helps appetite, energy, and digestion