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Combined oral contraceptive pills are often used to manage menstrual irregularity and androgen-related symptoms, while metformin is commonly prescribed to address insulin resistance and other metabolic issues ( 13 )

As a result, patients who utilize GLP-1 treatments typically experience reduced calorie intake and gradual, sustainable weight loss

When estrogen levels drop, bad cholesterol (LDL and triglycerides) tends to rise, good cholesterol (HDL) can fall, and insulin resistance increases, she says

Eng J, Kleinman WA, Singh L, Singh G, Raufman JP (1992) Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom