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Since it was based on mathematical modelling, our weight loss efficacy predictions require empirical validation

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For a 250 lb patient, high-dose sema-bima was like losing 50 lbs, but 45 lb of fat

Clinical trials on the safety and efficacy of semaglutide were developed around weekly dosing schedules

Cell 55 , 281290 (1988)

For example, a provider might design a plan that looks like this: Weeks 1-3: 1.5 mg per week Weeks 4-6: 3 mg per week Weeks 7-9: 6 mg per week Weeks 10-12: 9 mg per week And so on, continuing to titrate as determined by your provider, potentially up to a maximum of 13.5 mg per week