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However, future studies are needed to explore the pathophysiology of GLP-1RAs in individuals with type 2 diabetes and NAFLD and to determine the optimal use of GLP-1RAs to prevent adverse CVEs

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Once the first insulin radioimmunoassays (RIA) became available in the 1960's [58,59], the insulinotropic action of intestinal mucosa extracts was confirmed in healthy humans and was demonstrated to be absent in individuals with type-1 diabetes [60]
Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: incretin actions beyond the pancreas
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