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Patients with slow dose increase stayed with the plan more

In January 2025, the FTC released a second interim staff report finding the Big 3 PBMs marked up specialty generic drugs by thousands of percent, generating over $7.3 billion in excess revenue from 20172022 ( [45] )

Another barrier is storage and transportation

Pharmacies are typically required to counsel patients on medications they receive

And not just because of the significant weight loss

First, the analysis was based on a limited number of phase 1 and 2 RCTs, different retatrutide doses and populations, which may influence the effect size found in our results