generations of glp 1 agonists List GLP-1 Receptor for Diabetes & Weight Loss GLP-1 agonists for weight loss:

When used consistently, these medications slow down digestion and enhance feelings of fullness, helping individuals naturally reduce calorie intake without feeling deprived

GLP-1 controls the glucose level by stimulating insulin secretion, inhibiting glucagon secretion, and modulating gastric emptying, thus contributing to an enhancement of bone formation (35)

Glp1r expression is undetectable by quantitative PCR in peritoneal or adipose tissue macrophages (37), although Lyz2 -Credriven deletion of Glp1r ( Glp1r Lyz2/ ) abolishes expression in bone marrowderived macrophages (38)

doi: 10.1016/j.jdiacomp.2014.01.012

No significant drug interactions have been identified between GLP-1 receptor agonists and standard autoimmune medications including methotrexate, biologics (TNF inhibitors, IL-6 inhibitors), JAK inhibitors, or hydroxychloroquine

You had relatively modest GLP-1 exposure, and starting at the standard introductory dose is prudent