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Learn the pros, risks, and who may benefit.

Nevertheless, the overall drug exposure was not considered clinically significant

While these therapies reduce mortality and hospitalizations in HFrEF, their benefit in patients with heart failure with left ventricular ejection fraction (LVEF)40% remains less conclusive

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While the FDA says compounded drugs can serve an important medical need for patients, the agency does not approve these new formulations, increasing the risk of complications.

Data from cardiovascular outcomes trials and real-world studies demonstrate consistent benefits of combination therapy across diverse subpopulations, including those with established atherosclerotic cardiovascular disease or chronic kidney disease