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[DOI] [PubMed] [Google Scholar] 8.Meier JJ

The fatty tissue absorbs the medication slowly and steadily, which is what allows some of these drugs to work over the course of a full week from a single dose

This is why low-carb diets are known as diuretics
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Metformin may modestly help preserve lean mass through its effects on AMPK activation in muscle tissue, though the evidence for this is preliminary
Updated August 21, 2016
