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GLP-1R was found in nigrostriatal neurons, and loss of these neurons is a feature of Parkinsons disease (PD)

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Products marketed as GLP-1 vitamins or GLP-1 boosters typically contain ingredients that may marginally increase natural GLP-1 production, but the magnitude of effect does not approach what prescription medications achieve

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In vitro cell therapy also indicated that infusion of Treg cells could increase the expression of anti-inflammatory factors (such as IL-10, IL-4, TGF-, IL-2), while reducing the levels of pro-inflammatory factors (such as IL-17, IFN-) (94)