oral glp 1 drugs in development GLP-1 Medication Helps Patients Maintain Weight Loss | Research Trends in the Development of

GLP-1 agonists have been used as a treatment for type 2 diabetes for nearly two decades

Goncalves E, Bell DSH

At the same time, the data imply that a medicinal chemistry campaign focusing on engineering pharmacokinetically optimized GLP-1MK-801 conjugates might give rise to drugs that could outperform the current incretin-based treatments for obesity, such as semaglutide and tirzepatide

When combined with pharmacotherapy, these strategies provide a comprehensive approach to care

doi: 10.1089/chi.2022.0062

[DOI] [PMC free article] [PubMed] [Google Scholar] 584.Gerich J.E., Lorenzi M., Schneider V., Karam J.H., Rivier J., Guillemin R