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Description
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Tirzepatide is the first in this class to receive FDA approval, and it targets both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
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Despite their powerful weightloss efficacy, newer OMMs may take longer to achieve full weightloss benefit given their recommended dose titration schedule, which may take up to 20 weeks to reach the maximum dose
Additionally, some patients reduce caffeine consumption as appetite decreases, and caffeine withdrawal is a well-documented migraine precipitant
The typical concentration ranges from 0.5mg to 1mg per vial
