off label use of semaglutide Edit for clarity: THIS POST IS RESPONDING TO THE RECENT UPTICK IN DEMAND FOR OZEMPIC FOR VANITY-RELATED WEIGHT LOSS, NOT CLINICAL REASONS, DUE TO SOCIAL MEDIA. In 2017, the FDA approved Ozempic ( Off-Label Prescribing and Dispensing: Ozempic,

Additionally, it is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m or greater (Obesity) or 27 kg/m or greater (Overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)

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Efficacy comparison Injectable semaglutide has the strongest evidence base

When properly stored in a refrigerator at the advised temperature and assuming the cold chain remains intact, semaglutide remains effective until the expiration date provided by the manufacturer , which typically ranges from several months to a year after purchase