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Abstract A relatively recent addition to the arsenal of antidiabetic drugs used for the treatment of type 2 diabetes mellitus (T2DM) has been the incretin mimetics, a group of drugs that work on the glucagon-like peptide-1 (GLP-1) receptor and enhance insulin secretion from the pancreatic -cells in a glucose-dependent manner, more potently in hyperglycemic conditions, while suppressing glucagon secretion at the same time
Trahair LG, Horowitz M, Jones KL
10.2337/dc12-0709
In contrast to liraglutides potent effect in reducing food intake, the effects of FGF21 on food intake were less pronounced (Fig
administration of d-allulose did not change blood glucose levels at 0 min in fasted (16 h) HFD-fed mice (Fig
