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Description
Dual- and multi-receptor agonists may be a novel drug class to treat obesity and type 2 diabetes mellitus with high efficacy.

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Orlistat (Alli), Sibutramine (Meridia), and Rimonabant (Acomplia) emerged, but some were banned due to cardiovascular and mental health risks

Results Twelve studies met inclusion criteriaeight human and four preclinical

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Evidence, safety, and NHS treatment pathways explained.
