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Cannabis use has increased in recent years, coinciding with more countries legalizing cannabis for both recreational and medicinal purposes

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In vitro, mouse pancreatic -cells (NIT-1 cells) were exposed to palmitic acid (PA), PA+exendin-4 (Ex-4), PA+GW, PA+GSK0660 (GSK, a PPAR antagonist), or PA+Ex-4+GSK

This narrative reviewaims to analyzecurrent findings on the beneficial and adverse ocular effects of GLP-1RAsuse, highlighting studies that elucidate the harmful causes, such as retinal microvascular dysregulation, inflammatory modulation, oxidative stress,osmotic dysregulation from sorbitol accumulation,and metabolic shifts

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