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While the mechanisms differ from tirzepatide, the clinical outcomes are comparable for most patients with type 2 diabetes

Contrave is a prescription combination of naltrexone and bupropion that targets two areas of the brain involved in appetite and cravings: Bupropion activates neurons in the hypothalamus that naturally suppress appetite -Naltrexone blocks the brains counter-signal that would normally mute that appetite suppression Together, they keep the appetite-reducing effect switched on longer than either drug achieves alone The result is a reduction in food cravings, less reward-seeking behavior around eating, and for many patients, a quieter mental relationship with food without relying on stimulants or gut hormone changes.Heres the key mechanism: the hypothalamus is the part of your brain that regulates appetite and energy balance

The right choice depends on your injection volume, which depends on your dose and the concentration of your compounded tirzepatide

New England Journal of Medicine (2021) This head-to-head comparison trial randomized 1,879 patients with type 2 diabetes to tirzepatide (5mg, 10mg, or 15mg weekly) or semaglutide 1mg weekly for 40 weeks

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