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Cutcliffe recalls "getting rejected up and down Silicon Valley" , but she persevered, and with seed capital from the Mayo Clinic, Pendulum was able to engineer its own oxygen-free fermentation process to manufacture Akkermansia as well as other proprietary strains

Now both of those are trending in the opposite direction: The drugs are becoming more affordable, and according to the data, the stigma around using these medicines may not be as stifling as it used to be

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